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BMCBI
2004
111views more  BMCBI 2004»
13 years 7 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
BMCBI
2010
72views more  BMCBI 2010»
13 years 7 months ago
Potentials 'R'Us web-server for protein energy estimations with coarse-grained knowledge-based potentials
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
Yaping Feng, Andrzej Kloczkowski, Robert L. Jernig...
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 7 months ago
Globally, unrelated protein sequences appear random
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
Daniel T. Lavelle, William R. Pearson
BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...