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» Predicting protein function from domain content
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BIOINFORMATICS
2008
135views more  BIOINFORMATICS 2008»
13 years 7 months ago
Message-passing algorithms for the prediction of protein domain interactions from protein-protein interaction data
Motivation: Cellular processes often hinge upon specific interactions among proteins, and knowledge of these processes at a system level constitutes a major goal of proteomics. In...
Mudassar Iqbal, Alex Alves Freitas, Colin G. Johns...
LION
2009
Springer
112views Optimization» more  LION 2009»
14 years 1 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
BMCBI
2008
145views more  BMCBI 2008»
13 years 7 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
NAR
2007
90views more  NAR 2007»
13 years 7 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
CANDC
2008
ACM
13 years 7 months ago
In silico identification of the protein disulfide isomerase family from a protozoan parasite
Protein disulfide isomerase (PDI) enzymes are eukaryotic oxidoreductases that catalyze the correct formation of disulfide bonds during protein folding. Structurally they are chara...
Marco A. Ramos, Rosa E. Mares, Paloma D. Maga&ntil...