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BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
13 years 7 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
BMCBI
2010
13 years 7 months ago
2010
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
BMCBI
2008
13 years 7 months ago
2008
Background: There has been recent concern regarding the inability of predictive modeling approaches to generalize to new data. Some of the problems can be attributed to improper m...
BMCBI
2006
13 years 7 months ago
2006
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
VLDB
2002
ACM
13 years 7 months ago
2002
ACM
Automated recommendation (e.g., personalized product recommendation on an ecommerce web site) is an increasingly valuable service associated with many databases--typically online ...