175 search results - page 19 / 35 » Predicting the Effects of Gene Deletion |
BMCBI
2010
2010
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
13 years 7 months ago
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
BMCBI
2006
13 years 7 months ago
2006
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
BMCBI
2006
13 years 7 months ago
2006
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
BMCBI
2010
13 years 4 months ago
2010
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
BMCBI
2008
13 years 7 months ago
2008
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...