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» Predicting the Effects of Gene Deletion
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BMCBI
2010
163views more  BMCBI 2010»
13 years 2 months ago
RISCI - Repeat Induced Sequence Changes Identifier: a comprehensive, comparative genomics-based, in silico subtractive hybridiza
Background -: The availability of multiple whole genome sequences has facilitated in silico identification of fixed and polymorphic transposable elements (TE). Whereas polymorphic...
Vipin Singh, Rakesh K. Mishra
BMCBI
2010
126views more  BMCBI 2010»
13 years 7 months ago
Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data
Background: The enumeration of tetrameric and other sequence motifs that are positively or negatively correlated with in vivo antisense DNA effects has been a useful addition to t...
Donald M. Gray, Carla W. Gray, Byong-Hoon Yoo, Tzu...
BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
BMCBI
2005
107views more  BMCBI 2005»
13 years 7 months ago
A stepwise framework for the normalization of array CGH data
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
Mehrnoush Khojasteh, Wan L. Lam, Rabab Kreidieh Wa...
BMCBI
2005
104views more  BMCBI 2005»
13 years 7 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...