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AIME
2009
Springer
13 years 11 months ago
Effect of Background Correction on Cancer Classification with Gene Expression Data
This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays...
Adelaide Freitas, Gladys Castillo, Ana São ...
CPM
2000
Springer
141views Combinatorics» more  CPM 2000»
13 years 11 months ago
A Lower Bound for the Breakpoint Phylogeny Problem
Breakpoint phylogenies methods have been shown to be an effective way to extract phylogenetic information from gene order data. Currently, the only practical breakpoint phylogeny a...
David Bryant
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2011
12 years 11 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
BMCBI
2006
160views more  BMCBI 2006»
13 years 7 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...