Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
Background: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these...
Interactive programs, such as GUIs or spreadsheets, often maintain dependency information over dynamically-created networks of objects. That is, each imperative object tracks not ...
Neel R. Krishnaswami, Lars Birkedal, Jonathan Aldr...