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JUCS
2010
104views more  JUCS 2010»
13 years 7 months ago
Investigating a Correlation between Subcellular Localization and Fold of Proteins
: When considering the prediction of a structural class for a protein as a classification problem, usually a classifier is based on a feature vector x ∈ Rn , where the features...
Johannes Aßfalg, Jing Gong, Hans-Peter Krieg...
BMCBI
2007
128views more  BMCBI 2007»
13 years 8 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
14 years 2 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2010
183views more  BMCBI 2010»
13 years 8 months ago
Active learning for human protein-protein interaction prediction
Background: Biological processes in cells are carried out by means of protein-protein interactions. Determining whether a pair of proteins interacts by wet-lab experiments is reso...
Thahir P. Mohamed, Jaime G. Carbonell, Madhavi Gan...