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BMCBI
2006
114views more  BMCBI 2006»
13 years 7 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
LION
2009
Springer
112views Optimization» more  LION 2009»
14 years 2 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
RECOMB
2001
Springer
14 years 7 months ago
Towards predicting coiled-coil protein interactions
Protein-protein interactions play a central role in many cellular functions, and as whole-genome data accumulates, computational methods for predicting these interactions become i...
Mona Singh, Peter S. Kim
BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...