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BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 7 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2010
176views more  BMCBI 2010»
13 years 7 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
NIPS
2008
13 years 9 months ago
Stochastic Relational Models for Large-scale Dyadic Data using MCMC
Stochastic relational models (SRMs) [15] provide a rich family of choices for learning and predicting dyadic data between two sets of entities. The models generalize matrix factor...
Shenghuo Zhu, Kai Yu, Yihong Gong
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...