Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
The TaskTracer system allows knowledge workers to define a set of activities that characterize their desktop work. It then associates with each user-defined activity the set of ...
Jianqiang Shen, Jed Irvine, Xinlong Bao, Michael G...
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
Ultrasound has become a useful tool for speech scientists studying mechanisms of language sound production. State-of-the-art methods for extracting tongue contours from ultrasound...