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BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
BMCBI
2010
123views more  BMCBI 2010»
13 years 2 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
NAR
2007
90views more  NAR 2007»
13 years 7 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
BMCBI
2004
108views more  BMCBI 2004»
13 years 7 months ago
Enhanced protein domain discovery using taxonomy
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
Lachlan James M. Coin, Alex Bateman, Richard Durbi...
NAR
2008
103views more  NAR 2008»
13 years 7 months ago
DBD--taxonomically broad transcription factor predictions: new content and functionality
DNA-binding domain (DBD) is a database of predicted sequence-specific DNA-binding transcription factors (TFs) for all publicly available proteomes. The proteomes have increased fr...
Derek Wilson, Varodom Charoensawan, Sarah K. Kumme...