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» Prediction of indirect interactions in proteins
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BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2005
130views more  BMCBI 2005»
13 years 7 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
BMCBI
2011
13 years 2 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
ICCS
2007
Springer
14 years 1 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
NAR
2006
75views more  NAR 2006»
13 years 7 months ago
DrugBank: a comprehensive resource for in silico drug discovery and exploration
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical)data withcomprehensive drug target (i.e.protein) information. The database ...
David S. Wishart, Craig Knox, Anchi Guo, Savita Sh...