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» Prediction of protein structural class with Rough Sets
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BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
CSB
2005
IEEE
143views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Analysis of four different sets of predictive features for metalloproteins
Metals bound to the protein are important for functional or structural roles. Despite their importance there is a distinct lack of research for identification of metalloproteins f...
Huseyin Seker, Parvez I. Haris
BMCBI
2008
114views more  BMCBI 2008»
13 years 8 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
ICCCI
2009
Springer
14 years 3 months ago
Accuracy in Predicting Secondary Structure of Ionic Channels
Ionic channels are among the most difficult proteins for experimental structure determining, very few of them has been resolved. Bioinformatical tools has not been tested for this ...
Bogumil Konopka, Witold Dyrka, Jean-Christophe Neb...