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TCBB
2008
126views more  TCBB 2008»
13 years 7 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
BMCBI
2011
12 years 11 months ago
RAG: An Update to the RNA-As-Graphs Resource
Background: In 2004, we presented a web resource for stimulating the search for novel RNAs, RNA-As-Graphs (RAG), which classified, catalogued, and predicted RNA secondary structur...
Joseph A. Izzo, Namhee Kim, Shereef Elmetwaly, Tam...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BMCBI
2008
101views more  BMCBI 2008»
13 years 7 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BMCBI
2010
89views more  BMCBI 2010»
13 years 7 months ago
Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in gene
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
Antonio Deiana, Andrea Giansanti