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BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 7 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
IPPS
2007
IEEE
14 years 1 months ago
Protein Secondary Structure Prediction using Bayesian Inference method on Decision fusion algorithms
Prediction of protein secondary structure (alpha-helix, beta-sheet, coil) from primary sequence of amino acids is a very challenging task, and the problem has been approached from...
Somasheker Akkaladevi, Ajay K. Katangur
CEC
2005
IEEE
14 years 1 months ago
Evolving hidden Markov models for protein secondary structure prediction
New results are presented for the prediction of secondary structure information for protein sequences using Hidden Markov Models (HMMs) evolved using a Genetic Algorithm (GA). We a...
Kyoung-Jae Won, Thomas Hamelryck, Adam Prügel...
BMCBI
2010
145views more  BMCBI 2010»
13 years 2 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...