Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
Accurately predicting program behaviors (e.g., locality, dependency, method calling frequency) is fundamental for program optimizations and runtime adaptations. Despite decades of...
Kai Tian, Yunlian Jiang, Eddy Z. Zhang, Xipeng She...
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...