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BMCBI
2010
120views more  BMCBI 2010»
15 years 2 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
113
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BMCBI
2006
159views more  BMCBI 2006»
15 years 2 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
CGF
2006
263views more  CGF 2006»
15 years 2 months ago
A Predictive Light Transport Model for the Human Iris
Recently, light interactions with organic matter have become the object of detailed investigations by image synthesis researchers. Besides allowing these materials to be rendered ...
Michael W. Y. Lam, Gladimir V. G. Baranoski
109
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BMCBI
2010
129views more  BMCBI 2010»
15 years 2 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini
114
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BMCBI
2010
99views more  BMCBI 2010»
15 years 2 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...