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BMCBI
2006
118views more  BMCBI 2006»
13 years 8 months ago
Identification of gene expression patterns using planned linear contrasts
Background: In gene networks, the timing of significant changes in the expression level of each gene may be the most critical information in time course expression profiles. With ...
Hao Li, Constance L. Wood, Yushu Liu, Thomas V. Ge...
BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...
BMCBI
2010
153views more  BMCBI 2010»
13 years 6 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...