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BIODATAMINING
2008
140views more  BIODATAMINING 2008»
13 years 9 months ago
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics appr
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
BMCBI
2010
130views more  BMCBI 2010»
13 years 9 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
BMCBI
2008
92views more  BMCBI 2008»
13 years 9 months ago
OpenMS - An open-source software framework for mass spectrometry
Background: Mass spectrometry is an essential analytical technique for high-throughput analysis in proteomics and metabolomics. The development of new separation techniques, preci...
Marc Sturm, Andreas Bertsch, Clemens Gröpl, A...
BMCBI
2008
83views more  BMCBI 2008»
13 years 9 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...