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JIB
2007
95views more  JIB 2007»
13 years 10 months ago
Mining for Single Nucleotide Polymorphisms in Expressed Sequence Tags
As a multitude of sequence data are published, discovering polymorphisms bioinformatically becomes a valid option. In silico Single Nucleotide Polymorphism (SNP) detection is base...
E. L. Souche, B. Hellemans, J. K. J. Van Houdt, A....
BMCBI
2004
114views more  BMCBI 2004»
13 years 10 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
97views more  BMCBI 2004»
13 years 10 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
BMCBI
2004
104views more  BMCBI 2004»
13 years 10 months ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...
BMCBI
2004
93views more  BMCBI 2004»
13 years 10 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...