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JIB
2006
106views more  JIB 2006»
13 years 9 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 12 months ago
On the Role of Local Matching for Efficient Semi-supervised Protein Sequence Classification
Recent studies in protein sequence analysis have leveraged the power of unlabeled data. For example, the profile and mismatch neighborhood kernels have shown significant improveme...
Pavel P. Kuksa, Pai-Hsi Huang, Vladimir Pavlovic
RIVF
2008
13 years 11 months ago
Speeding up subset seed algorithm for intensive protein sequence comparison
Abstract--Sequence similarity search is a common and repeated task in molecular biology. The rapid growth of genomic databases leads to the need of speeding up the treatment of thi...
Van Hoa Nguyen, Dominique Lavenier
NAR
2006
119views more  NAR 2006»
13 years 9 months ago
ChloroplastDB: the Chloroplast Genome Database
The Chloroplast Genome Database (ChloroplastDB) is an interactive, web-based database for fully sequenced plastid genomes, containing genomic, protein, DNA and RNA sequences, gene...
Liying Cui, Narayanan Veeraraghavan, Alexander Ric...
BMCBI
2008
140views more  BMCBI 2008»
13 years 10 months ago
FUNYBASE: a FUNgal phYlogenomic dataBASE
Background: The increasing availability of fungal genome sequences provides large numbers of proteins for evolutionary and phylogenetic analyses. However the heterogeneity of data...
Sylvain Marthey, Gabriela Aguileta, Françoi...