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BMCBI
2006
159views more  BMCBI 2006»
13 years 9 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...
NAR
2007
120views more  NAR 2007»
13 years 9 months ago
TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT method
TOPOFIT-DB (T-DB) is a public web-based database of protein structural alignments based on the TOPOFIT method, providing a comprehensive resource for comparative analysis of prote...
Chesley M. Leslin, Alexej Abyzov, Valentin A. Ilyi...
BMCBI
2010
123views more  BMCBI 2010»
13 years 4 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
NAR
1998
161views more  NAR 1998»
13 years 9 months ago
Touring protein fold space with Dali/FSSP
The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is deriv...
Liisa Holm, Chris Sander