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IJDMB
2011
129views more  IJDMB 2011»
12 years 10 months ago
Modelling gene and protein regulatory networks with Answer Set Programming
: Recently, many approaches to model regulatory networks have been proposed in the systems biology domain, however the task is far from being solved. In this paper we propose an an...
Timur Fayruzov, Jeroen Janssen, Dirk Vermeir, Chri...
JCB
2002
131views more  JCB 2002»
13 years 7 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
BIOINFORMATICS
2005
152views more  BIOINFORMATICS 2005»
13 years 7 months ago
Intervention in context-sensitive probabilistic Boolean networks
Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...
TSP
2008
134views more  TSP 2008»
13 years 6 months ago
Effect of Function Perturbation on the Steady-State Distribution of Genetic Regulatory Networks: Optimal Structural Intervention
Abstract--The dynamics of a rule-based gene regulatory network are determined by the regulatory functions in conjunction with whatever probability distributions are involved in net...
Xiaoning Qian, Edward R. Dougherty
CEC
2003
IEEE
13 years 11 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles