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BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
13 years 8 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
BMCBI
2005
82views more  BMCBI 2005»
13 years 8 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
JWSR
2007
172views more  JWSR 2007»
13 years 8 months ago
Service Class Driven Dynamic Data Source Discovery with DynaBot
: Dynamic Web data sources – sometimes known collectively as the Deep Web – increase the utility of the Web by providing intuitive access to data repositories anywhere that Web...
Daniel Rocco, James Caverlee, Ling Liu, Terence Cr...
BMCBI
2010
81views more  BMCBI 2010»
13 years 8 months ago
Empirical Bayes Analysis of Sequencing-based Transcriptional Profiling without Replicates
Background: Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based tran...
Zhijin Wu, Bethany D. Jenkins, Tatiana A. Rynearso...
BMCBI
2008
166views more  BMCBI 2008»
13 years 7 months ago
QuantPrime - a flexible tool for reliable high-throughput primer design for quantitative PCR
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
Samuel Arvidsson, Miroslaw Kwasniewski, Diego Maur...