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170
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BMCBI
2008
15 years 4 months ago
2008
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
140
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BMCBI
2008
15 years 4 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
149
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AEI
2006
15 years 4 months ago
2006
This paper presents a linguistic framework for developing a formal knowledge acquisition method. The framework is intended to empower domain experts to specify information require...
143
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BMCBI
2006
15 years 4 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
147
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BMCBI
2006
15 years 4 months ago
2006
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...