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BMCBI
2008
15 years 4 months ago
2008
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
137
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BMCBI
2006
15 years 4 months ago
2006
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
160
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BMCBI
2006
15 years 4 months ago
2006
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
130
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BMCBI
2006
15 years 4 months ago
2006
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
149
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BMCBI
2006
15 years 4 months ago
2006
Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary f...