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BMCBI
2010
13 years 10 months ago
2010
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
BMCBI
2008
13 years 10 months ago
2008
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
BMCBI
2008
13 years 10 months ago
2008
Background: Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples. The analysis of t...
BMCBI
2008
13 years 10 months ago
2008
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
BMCBI
2006
13 years 9 months ago
2006
Background: The increasing availability of time-series expression data opens up new possibilities to study functional linkages of genes. Present methods used to infer functional l...