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» Progressive multiple sequence alignments from triplets
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BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2011
13 years 2 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...
CF
2007
ACM
13 years 11 months ago
Parallel genomic sequence-search on a massively parallel system
In the life sciences, genomic databases for sequence search have been growing exponentially in size. As a result, faster sequencesearch algorithms to search these databases contin...
Oystein Thorsen, Brian E. Smith, Carlos P. Sosa, K...
BMCBI
2005
108views more  BMCBI 2005»
13 years 7 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2011
13 years 2 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng