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BMCBI
2006
123views more  BMCBI 2006»
13 years 6 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
CVPR
2010
IEEE
14 years 2 months ago
Pareto Discriminant Analysis
Linear Discriminant Analysis (LDA) is a popular tool for multiclass discriminative dimensionality reduction. However, LDA suffers from two major problems: (1) It only optimizes th...
Karim Abou-Moustafa, Fernando De la Torre, Frank F...
EKAW
2008
Springer
13 years 8 months ago
Principles for Knowledge Engineering on the Web
With the advent of the Web and the efforts towards a Semantic Web the nature of knowledge engineering has changed drastically. In this position paper we propose four principles fo...
Guus Schreiber
ECIS
2004
13 years 8 months ago
Measuring enterprise systems success: the importance of a multiple stakeholder perspective
: Organisations invest enormous amount of resources in acquiring Enterprise Systems (ES), presumably expecting positive impacts to the organisation and its functions. Despite the o...
Darshana Sedera, Guy G. Gable, Taizan Chan
ISMB
1997
13 years 8 months ago
Standardized Representations of the Literature: Combining Diverse Sources of Ribosomal Data
We are building a knowledge base (KB) of published structural data on the 30s ribosomal subunit in prokaryotes. Our KB is distinguished by a standardized representation of biologi...
Russ B. Altman, Neil F. Abernethy, Richard O. Chen