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BMCBI
2010
139views more  BMCBI 2010»
13 years 9 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
123views more  BMCBI 2008»
13 years 9 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
SIGGRAPH
2000
ACM
14 years 1 months ago
The digital Michelangelo project: 3D scanning of large statues
We describe a hardware and software system for digitizing the shape and color of large fragile objects under non-laboratory conditions. Our system employs laser triangulation rang...
Marc Levoy, Kari Pulli, Brian Curless, Szymon Rusi...
BMCBI
2011
13 years 3 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...