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INFSOF
2007
126views more  INFSOF 2007»
13 years 7 months ago
Software maintenance seen as a knowledge management issue
Creating and maintaining software systems is a knowledge intensive task. One needs to have a good understanding of the application domain, the problem to solve and all its require...
Nicolas Anquetil, Káthia Marçal de O...
BMCBI
2005
130views more  BMCBI 2005»
13 years 7 months ago
Squid - a simple bioinformatics grid
Background: BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled &...
Paulo C. Carvalho, Rafael V. Glória, Antoni...
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
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