We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
The most suitable method for the automated classification of protein structures remains an open problem in computational biology. In order to classify a protein structure with an...