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BMCBI
2008
94views more  BMCBI 2008»
13 years 7 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
NAR
2006
120views more  NAR 2006»
13 years 7 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...
BMCBI
2010
172views more  BMCBI 2010»
13 years 2 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
NAACL
2010
13 years 5 months ago
Joint Inference for Knowledge Extraction from Biomedical Literature
Knowledge extraction from online repositories such as PubMed holds the promise of dramatically speeding up biomedical research and drug design. After initially focusing on recogni...
Hoifung Poon, Lucy Vanderwende