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» Protein complex prediction via cost-based clustering
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BMCBI
2004
153views more  BMCBI 2004»
13 years 7 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
JCB
2007
83views more  JCB 2007»
13 years 7 months ago
Evolutionary Networks in the Formatted Protein Sequence Space
In our recent work, a new approach to establish sequence relatedness, by walking through the protein sequence space, was introduced. The sequence space is built from 20 amino acid...
Zakharia M. Frenkel, Edward N. Trifonov
CORR
2010
Springer
144views Education» more  CORR 2010»
13 years 7 months ago
CLP-based protein fragment assembly
Abstract. The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments ar...
Alessandro Dal Palù, Agostino Dovier, Feder...
BMCBI
2010
159views more  BMCBI 2010»
13 years 7 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao