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» Protein complex prediction via cost-based clustering
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BIBE
2010
IEEE
181views Bioinformatics» more  BIBE 2010»
13 years 8 months ago
Multi Level Clustering of Phylogenetic Profiles
The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to in...
Fotis E. Psomopoulos, Pericles A. Mitkas
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
AMAI
2004
Springer
14 years 27 days ago
Bayesian Model Averaging Across Model Spaces via Compact Encoding
Bayesian Model Averaging (BMA) is well known for improving predictive accuracy by averaging inferences over all models in the model space. However, Markov chain Monte Carlo (MCMC)...
Ke Yin, Ian Davidson
NAR
2008
138views more  NAR 2008»
13 years 7 months ago
TarO: a target optimisation system for structural biology
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 7 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li