Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Each yearpeoplespendahugeamountoftimetyping. Thetextpeopletype typically contains a tremendousamount of redundancy due to predictable word usage patterns and the text's struc...
Distributed Genetic Algorithm (DGA) is one of the most promising choices among the optimization methods. In this paper we describe DGAFrame, a flexible framework for evolutionary...