The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Protein structure determination and prediction has been a focal research subject in life sciences due to the importance of protein structure in understanding the biological and ch...
Predicting protein secondary structure is a key step in determining the 3D structure of a protein that determines its function. The Dictionary of Secondary Structure of Proteins (...
Background: Residue depth allows determining how deeply a given residue is buried, in contrast to the solvent accessibility that differentiates between buried and solvent-exposed ...
Hua Zhang, Tuo Zhang, Ke Chen 0003, Shiyi Shen, Ji...
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...