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BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
HotSwap for bioinformatics: A STRAP tutorial
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
Christoph Gille, Peter N. Robinson
JMLR
2012
11 years 10 months ago
Active Clustering of Biological Sequences
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
CORR
2010
Springer
157views Education» more  CORR 2010»
13 years 7 months ago
Efficient Clustering with Limited Distance Information
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model ...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
CPHYSICS
2006
204views more  CPHYSICS 2006»
13 years 7 months ago
Genetically controlled random search: a global optimization method for continuous multidimensional functions
A new stochastic method for locating the global minimum of a multidimensional function inside a rectangular hyperbox is presented. A sampling technique is employed that makes use ...
Ioannis G. Tsoulos, Isaac E. Lagaris
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 7 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki