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» Protein structure alignment using elastic shape analysis
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BMCBI
2005
108views more  BMCBI 2005»
13 years 8 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
ISVC
2009
Springer
14 years 3 months ago
Wavelet-Based Representation of Biological Shapes
Modeling, characterization and analysis of biological shapes and forms are important in many computational biology studies. Shape representation challenges span the spectrum from s...
Bin Dong, Yu Mao, Ivo D. Dinov, Zhuowen Tu, Yongga...
BMCBI
2005
125views more  BMCBI 2005»
13 years 8 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2010
201views more  BMCBI 2010»
13 years 8 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...