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BMCBI
2010
80views more  BMCBI 2010»
13 years 7 months ago
Sampling the conformation of protein surface residues for flexible protein docking
Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Identification of NAD interacting residues in proteins
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
Hifzur Rahman Ansari, Gajendra P. S. Raghava
RECOMB
2002
Springer
14 years 8 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...
PR
2006
84views more  PR 2006»
13 years 7 months ago
Clustering techniques for protein surfaces
Though most approaches to protein comparison are based on their structure, several studies produced evidence of a strict correlation between the surface characteristics of protein...
Lorenzo Baldacci, Matteo Golfarelli, Alessandra Lu...
NIPS
2007
13 years 9 months ago
A learning framework for nearest neighbor search
Can we leverage learning techniques to build a fast nearest-neighbor (ANN) retrieval data structure? We present a general learning framework for the NN problem in which sample que...
Lawrence Cayton, Sanjoy Dasgupta