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KDD
2003
ACM
142views Data Mining» more  KDD 2003»
14 years 8 months ago
Frequent-subsequence-based prediction of outer membrane proteins
A number of medically important disease-causing bacteria (collectively called Gram-negative bacteria) are noted for the extra "outer" membrane that surrounds their cell....
Rong She, Fei Chen 0002, Ke Wang, Martin Ester, Je...
ISMB
2000
13 years 9 months ago
Accelerating Protein Classification Using Suffix Trees
Position-specific scoring matrices have been used extensively to recognize highly conserved protein regions. We present a method for accelerating these searches using a suffix tre...
Bogdan Dorohonceanu, Craig G. Nevill-Manning
RECOMB
2003
Springer
14 years 8 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
GECCO
2004
Springer
119views Optimization» more  GECCO 2004»
14 years 1 months ago
Randomized Local Search, Evolutionary Algorithms, and the Minimum Spanning Tree Problem
Randomized search heuristics, among them randomized local search and evolutionary algorithms, are applied to problems whose structure is not well understood, as well as to problems...
Frank Neumann, Ingo Wegener
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...