Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...