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IJCAI
2001
14 years 12 days ago
Qualitative Simulation of Genetic Regulatory Networks: Method and Application
Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simu...
Hidde de Jong, Michel Page, Céline Hernande...
JCB
2002
131views more  JCB 2002»
13 years 10 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
FORMATS
2007
Springer
14 years 5 months ago
On Timed Models of Gene Networks
Abstract. We present a systematic translation from timed models of genetic regulatory networks into products of timed automata to which one can apply verification tools in order l...
Grégory Batt, Ramzi Ben Salah, Oded Maler
ECAI
2008
Springer
14 years 24 days ago
Temporal Logic Patterns for Querying Qualitative Models of Genetic Regulatory Networks
Formal verification based on model checking provides a powerful technology to query qualitative models of dynamical systems. The application of model-checking approaches is hamper...
Pedro T. Monteiro, Delphine Ropers, Radu Mateescu,...
AB
2008
Springer
14 years 5 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte