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» Qualitative Simulation of Genetic Regulatory Networks: Metho...
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CCE
2005
13 years 7 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
RECOMB
2005
Springer
14 years 7 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...

Publication
303views
12 years 5 months ago
Evolutionary synthesis of analog networks
he significant increase in the available computational power that took place in recent decades has been accompanied by a growing interest in the application of the evolutionary ap...
Claudio Mattiussi