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» Quality Assessment of Peptide Tandem Mass Spectra
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BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
RECOMB
2005
Springer
14 years 7 months ago
A Hidden Markov Model Based Scoring Function for Mass Spectrometry Database Search
An accurate scoring function for database search is crucial for peptide identification using tandem mass spectrometry. Although many mathematical models have been proposed to scor...
Yunhu Wan, Ting Chen
BMCBI
2005
121views more  BMCBI 2005»
13 years 7 months ago
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) ma
Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...
CBMS
2007
IEEE
14 years 1 months ago
MS2DB: A Mass-Based Hashing Algorithm for the Identification of Disulfide Linkage Patterns in Protein Utilizing Mass Spectrometr
The tertiary structure and biological function of a protein can be better understood given knowledge of the number and location of its disulfide bonds. By utilizing mass spectrome...
Timothy Lee, Rahul Singh, Ten-Yang Yen, Bruce Mach...
BMCBI
2004
159views more  BMCBI 2004»
13 years 7 months ago
Extractor for ESI quadrupole TOF tandem MS data enabled for high throughput batch processing
Background: Mass spectrometry based proteomics result in huge amounts of data that has to be processed in real time in order to efficiently feed identification algorithms and to e...
Andreas M. Boehm, Robert P. Galvin, Albert Sickman...