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BMCBI
2010
123views more  BMCBI 2010»
13 years 2 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 8 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
ISMIR
2004
Springer
138views Music» more  ISMIR 2004»
14 years 1 months ago
MusicBLAST - Gapped Sequence Alignment for MIR
We propose an algorithm, MusicBLAST, for approximate pattern search/matching on symbolic musical data. MusicBLAST is based on the BLAST algorithm, one of the most commonly used al...
Jürgen Kilian, Holger H. Hoos
BMCBI
2008
164views more  BMCBI 2008»
13 years 8 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
ICSM
2007
IEEE
14 years 2 months ago
A Maintainable Software Architecture for Fast and Modular Bioinformatics Sequence Search
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
Jeremy S. Archuleta, Eli Tilevich, Wu-chun Feng