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BMCBI
2010
100views more  BMCBI 2010»
13 years 6 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BIBE
2007
IEEE
162views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
An Investigation into the Feasibility of Detecting Microscopic Disease Using Machine Learning
— The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. We are investigating the possibility of de...
Mary Qu Yang, Jack Y. Yang
BMCBI
2006
155views more  BMCBI 2006»
13 years 6 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
ISNN
2004
Springer
14 years 3 days ago
A Novel Clustering Analysis Based on PCA and SOMs for Gene Expression Patterns
This paper proposes a novel clustering analysis algorithm based on principal component analysis (PCA) and self-organizing maps (SOMs) for clustering the gene expression patterns. T...
Hong-Qiang Wang, De-Shuang Huang, Xing-Ming Zhao, ...
BMCBI
2006
174views more  BMCBI 2006»
13 years 6 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...