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BMCBI
2006
13 years 10 months ago
2006
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
BMCBI
2006
13 years 10 months ago
2006
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
BMCBI
2006
13 years 10 months ago
2006
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
BMCBI
2006
13 years 10 months ago
2006
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
BMCBI
2006
13 years 10 months ago
2006
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...