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BMCBI
2006
13 years 7 months ago
2006
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
BMCBI
2006
13 years 7 months ago
2006
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
BMCBI
2006
13 years 7 months ago
2006
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
BMCBI
2006
13 years 7 months ago
2006
Background: Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing...
BMCBI
2006
13 years 7 months ago
2006
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...